Certification Board of Infection Control and Epidemiology (CBIC) Practice Exam 2025 – The All-in-One Guide for Exam Success

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Why is povidone iodine unsafe for neonates or premature infants?

It can cause allergic reactions

It may lead to skin irritation

It may be absorbed resulting in thyroid dysfunction

Povidone iodine is considered unsafe for neonates and premature infants primarily because it can be absorbed into their bodies, leading to potential thyroid dysfunction. The concern is particularly significant due to the developing endocrine systems of these vulnerable populations. Iodine, when absorbed in excessive amounts, can interfere with the normal function of the thyroid gland, potentially causing conditions such as hypothyroidism or goiter in these infants.

This risk is compounded in premature infants who have thinner skin and a higher surface area-to-volume ratio, making them more susceptible to systemic absorption of topical agents. Hence, special caution is warranted when using antiseptic solutions like povidone iodine in this age group to avoid any detrimental effects on their health and development.

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It is ineffective against germs

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