Certification Board of Infection Control and Epidemiology (CBIC) Practice Exam 2025 – The All-in-One Guide for Exam Success

Question: 1 / 400

How can biofilms affect infection resistance?

They enhance the immune response

They increase antibiotic susceptibility

They provide a protective matrix for microorganisms

Biofilms play a significant role in infection resistance because they provide a protective matrix for microorganisms. When bacteria form biofilms, they aggregate and encase themselves in a self-produced extracellular polymeric substance (EPS) that can shield them from both the host's immune responses and antimicrobial agents. This matrix limits the penetration of antibodies and other immune cells, thereby reducing the effectiveness of the body's immune response. Additionally, the physical barrier created by the biofilm can impede the delivery of antibiotics, contributing to the overall persistence of the infection.

By creating this protective environment, biofilms can lead to chronic infections that are difficult to treat and eradicate. Understanding the nature of biofilms is essential for developing strategies to prevent and manage infections, particularly in medical settings where devices and implants are often associated with biofilm formation.

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They facilitate faster healing

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